Coming From Downtown Orlando Take I-4E, Use The Right 2 Lanes To Take Exit 101B-101C For Fl-417 Toward Sanford,Merge Onto Fl-417 Toll S, Take Exit 52 Toward W 25Th St/H E Thomas Jr Pkwy,Continue On W 25Th St. Drive To E 24Th St In Sanford, Use The Left 2 Lanes To Turn Left Onto W 25Th St/H E Thomas Jr Pkwy,Turn Left Onto Mellonville Ave,Turn Right Onto E 24Th St To 1313 E 24Th St Sanford, Fl 32771.